Correlations of endothelin-1 gene polymorphisms and hypertensive intracerebral hemorrhage.

Abstract excerpt

OBJECTIVE: The aim of this study was to investigate the correlations of endothelin-1 (ET-1) gene polymorphisms with the occurrence of hypertensive intracerebral hemorrhage (HICH). PATIENTS AND METHODS: In this case-control study, 100 HICH patients and 100 controls with matched race, age and gender were enrolled as research subjects. Single nucleotide polymorphisms (rs1920453, rs1022436 and rs1035627) in the...