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Article

The Association between Whole-Brain MR Spectroscopy and IDH Mutation Status in Gliomas.

Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Jan 2020

Goryawala Mohammed, Saraf-Lavi Efrat, Nagornaya Natalia, Heros Deborah, Komotar Ricardo, Maudsley Andrew A

Abstract excerpt

BACKGROUND AND PURPOSE: Mutations in isocitrate dehydrogenase (IDH) have a direct effect on gliomagenesis. The purpose of this study is to quantify differences in brain metabolites due to IDH mutations. METHODS: Magnetic Resonance Spectroscopic Imaging (MRSI) was performed in 35 patients with gliomas of different grade and varied IDH mutation status. Volumes of interest (VOIs) for active tumor (tVOI), peritumoral...

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Identifiers

PMID: 31868291
DOI: 10.1111/jon.12685
PMCID: PMC7485119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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