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Article

The response of hepatitis B virus genotype to interferon is associated with a mutation in the interferon-stimulated response element.

Medicine - 1 Dec 2019

Guo Yanan, Lu He, Xu Lei, Idris Nur Fazleen Binti, Li Yimin, Hu Jieli, Huang Ailong, Tu Zeng

Abstract excerpt

Genetic variation and genotype of Hepatitis B virus (HBV) are related to the efficiency of interferon alpha (IFN-α)-based antiviral therapy. However, the correlation of variation in interferon-stimulated response element (ISRE) and HBV genotype response to IFN-α therapy remains elusive.Differences of ISRE between genotype B and C HBV were explored using the HBV sequences retrieved from GenBank, and further...

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Identifiers

PMID: 31861015
DOI: 10.1097/MD.0000000000018442
PMCID: PMC6940054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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