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Article

[Interferon resistance and ISDR (interferon sensitivity determining region)].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 2006

Amemiya Fumitake, Maekawa Shinya, Enomoto Nobuyuki

Abstract excerpt

A region associated with sensitivity to interferon has been identified in the nonstructural protein 5A(NS5A) of hepatitis C virus(HCV) genotype 1b. The region spans amino acid residues 2209 to 2248(NS5A2209-2248). While complete response was not obtained in the patients with HCV whose NS5A2209-2248 sequences were identical to that of HCV-J (wild type), all patients with HCV of 4 to 11 amino acid substitutions...

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PMID: 16838640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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