Article
Analysis of mutations within the 5' untranslated region, interferon sensitivity region, and PePHD region as a function of response to interferon therapy in hepatitis C virus-infected patients in India.
Journal of clinical microbiology - 1 Mar 2006
Gupta Romi, Subramani Murugan, Khaja Mohammed N, Madhavi Chandra, Roy Swagata, Habibullah Chittoor M, Das Saumitra
Abstract excerpt
Mutations in several subgenomic regions have been implicated in influencing response to interferon therapy; however, a comprehensive picture of Indian patients was lacking. Based on the viral load and clinical factors, 10 out of 15 patients were found to be complete responders, whereas 5 patients were nonresponders. The pretreatment viral RNA load of the patients was found to be between 5.20 and 6.13 log10 IU/ml,...
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