Article
Response to antiviral treatment in patients infected with hepatitis B virus genotypes E-H.
Journal of medical virology - 1 Oct 2009
Erhardt Andreas, Göbel Thomas, Ludwig Amei, Lau George K K, Marcellin Patrick, van Bömmel Florian, Heinzel-Pleines Ulrike, Adams Ortwin, Häussinger Dieter
Abstract excerpt
No data on antiviral response of HBV genotypes E-H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E-H, 23 received interferon (IFN)-alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. HBV genotype was determined by direct sequencing of the HBV S gene. Sustained virological response in IFN-treated patients was...
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