Article
Novel HBV mutations and their value in predicting efficacy of conventional interferon.
Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Apr 2017
Wu Da-Xian, Fu Xiao-Yu, Gong Guo-Zhong, Sun Ke-Wei, Gong Huan-Yu, Wang Ling, Wu Juan, Tan De-Ming
Abstract excerpt
BACKGROUND: Accumulating studies assessing the impacts of hot spot mutations on conventional interferon (IFN) efficacy come to discrepant conclusions; studies regarding the mutations in S and RT regions are also unclear. The present study aimed to evaluate the impacts of HBV mutations on the efficacy of conventional IFN. METHODS: A total of 126 patients who received conventional IFN treatment for 48 weeks were...
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