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Article

A mutation in the interferon regulatory element of HBV may influence the response of interferon treatment in chronic hepatitis B patients.

Virology journal - 10 Jan 2012

Lu Jia-Jie, Chen En-Qiang, Yang Jia-Hong, Zhou Tao-You, Liu Li, Tang Hong

Abstract excerpt

BACKGROUND: A functional interferon regulatory element (IRE) has been found in the EnhI/X promoter region of hepatitis B virus (HBV) genome. The purpose of this study is to compare the gene order of responder and non-responder to interferon therapy in patients with chronic hepatitis B (CHB), so as to evaluate the relationship between IRE mutation and the response to interferon treatment for CHB patients. RESULTS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Viral

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 22233973
DOI: 10.1186/1743-422X-9-10
PMCID: PMC3287143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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