Article
Single-nucleotide polymorphism of rs7944135 (macrophage-expressed gene 1) is associated with hepatitis B surface antigen seroclearance in chronic hepatitis B infection: A cohort study.
Medicine - 1 Dec 2019
Irham Lalu Muhammad, Wong Henry Sung-Ching, Perwitasari Dyah Aryani, Chou Wan-Hsuan, Yang Hwai-I, Chang Wei-Chiao
Abstract excerpt
Clearance of the hepatitis B surface antigen (HBsAg) is the ultimate aim of treatment for patients with chronic hepatitis B (CHB) infection. Genetic, factor age, and gender were reported to be involved in the clearance of HBsAg. However, the rate of HBsAg seroclearance in CHB patients is still low globally and few of the single-nucleotide polymorphism (SNP) had been identified to associated with HBsAg...
Topics
- Adult
- Cohort Studies
- Confidence Intervals
- DNA, Viral
- Female
- Gene Expression Regulation
- Genotype
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Male
- Middle Aged