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Article

SPP1 polymorphisms associated with HBV clearance and HCC occurrence.

International journal of epidemiology - 1 Oct 2007

Shin Hyoung Doo, Park Byung Lae, Cheong Hyun Sub, Yoon Jung-Hwan, Kim Yoon Jun, Lee Hyo-Suk

Abstract excerpt

BACKGROUND: Secreted phosphoprotein-1 (SPP1) is a secreted arginine-glycine-aspartate (RGD)-containing phosphoprotein. SPP1 is overexpressed in metastatic hepatocellular carcinoma (HCC), and therefore could act as both a diagnostic marker and a potential therapeutic target for metastatic HCC. We investigated the genetic polymorphisms in SPP1 to determine whether it is a potential candidate gene for a host genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17496055
DOI: 10.1093/ije/dym093

Genes

SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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