Article
Single nucleotide polymorphisms of toll-like receptor 7 in hepatitis C virus infection patients from a high-risk chinese population.
Inflammation - 1 Feb 2015
Xue Xing-Xin, Gong Jian-Ming, Tang Shai-di, Gao Chun-Fang, Wang Jia-Jia, Cai Li, Wang Jie, Yu Rong-Bin, Peng Zhi-Hang, Fan Nai-Jun, Wang Chang-Jun, Zhu Jin, Zhang Yun
Abstract excerpt
Hepatitis C virus (HCV) infection varies in the outcomes depending on both viral and host factors. This study aims to investigate the associations of three single nucleotide polymorphisms (SNPs) of Toll-like receptor 7 (TLR7), rs179016, rs5743733, and rs1634323, with susceptibility to HCV infection and clearance. The three SNPs were genotyped in a high-risk Chinese population, including 444 HCV spontaneous...
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