Article
Polymorphism of PXR gene associated with the increased risk of drug-induced liver injury in Indonesian pulmonary tuberculosis patients.
Journal of clinical pharmacy and therapeutics - 1 Dec 2015
Zazuli Z, Barliana M I, Mulyani U A, Perwitasari D A, Ng H, Abdulah R
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: Tuberculosis is still a major infectious disease in Indonesia. Patients are treated mostly using fixed-dose combination treatment in primary public health facilities. The incidence of antituberculosis drug-induced liver injury (AT-DILI) is approximately 10% among Indonesian tuberculosis patients who used standard fixed combination regimens during the intensive phase of treatment....
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