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Article

A Whole-Exome Sequencing Study of Tourette Disorder in a Chinese Population.

DNA and cell biology - 1 Jan 2020

Zhao Xin, Wang Sheng, Hao Juanjuan, Zhu Pengcheng, Zhang Xin, Wu Min

Abstract excerpt

To investigate the contribution of de novo variants to Tourette disorder (TD) probands in China. Whole-exome sequencing (WES) conducted on 15 child-parent trios (45 samples) detected 25 coding de novo variants, including 2 de novo Likely Gene Disrupting (LGD) variants and 6 Missense3 variants. The de novo LGD variants were consistently associated with TD risk (Fisher's exact test OR 2.69; p = 0.1952), although...

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Identifiers

PMID: 31855460
DOI: 10.1089/dna.2019.4746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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