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Article

Tourette Syndrome and Chronic Tic Disorders.

The Psychiatric clinics of North America - 1 Jun 2025

Halvorsen Matthew W

Abstract excerpt

Tourette syndrome (TS) and chronic tic disorder (CTD) are characterized by persistent verbal and motor tics of varying severity. We describe modern genetic studies of TS/CTD focused on common and rare variation, which quantify genetic risk per patient and identify risk genes such as NRXN1 and CELSR3. In general, the burden of TS/CTD genetic risk correlates with tic severity and the likelihood of a case belonging...

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Source

Identifiers

PMID: 40348418
DOI: 10.1016/j.psc.2025.01.006

Genes

CELSR3
NRXN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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