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Article

Interleukin-1β (IL-1β) & IL-4 gene polymorphisms in patients with systemic lupus erythematosus (SLE) & their association with susceptibility to SLE.

The Indian journal of medical research - 1 May 2016

Mohammadoo-Khorasani Milad, Salimi Saeedeh, Tabatabai Ehsan, Sandoughi Mahnaz, Zakeri Zahra, Farajian-Mashhadi Farzaneh

Abstract excerpt

BACKGROUND & OBJECTIVES: Interleukin-1 (IL-1) is one of the pro-inflammatory cytokines that plays a main role in the regulation of immune and inflammatory responses. Interleukin 4 (IL-4) as an anti-inflammatory cytokine regulates balance between Th1 and Th2 immune responses. this study was undertaken to investigate the IL-1β and IL-4 genes polymorphisms in patients with systemic lupus erythematosus (SLE) and also...

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Identifiers

PMID: 27488002
DOI: 10.4103/0971-5916.187107
PMCID: PMC4989832

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