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Article

Association of interleukin-1 genetic polymorphisms with the risk of rheumatoid arthritis in Chinese population.

Clinical chemistry and laboratory medicine - 1 Jan 2007

You Chong-ge, Li Jian-feng, Xie Xiao-dong, Zhu Yan, Li Pei-qiang, Chen Yi-rong

Abstract excerpt

BACKGROUND: Previous studies suggest that a variable number of tandem repeats polymorphism in the second intron of the interleukin-1 receptor antagonist gene and two single nucleotide polymorphisms at positions -511 and +3954 of the interleukin-1beta (IL-1B) gene are associated with an increased risk of autoimmune diseases. In the present study, we evaluated associations between these genetic factors and an...

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Identifiers

PMID: 17867984
DOI: 10.1515/CCLM.2007.156

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