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Article

Gene-by-gene interactions associated with the risk of conotruncal heart defects.

Molecular genetics & genomic medicine - 1 Jan 2020

Lyu Chen, Webber Daniel M, MacLeod Stewart L, Hobbs Charlotte A, Li Ming

Abstract excerpt

BACKGROUND: The development of conotruncal heart defects (CTDs) involves a complex relationship among genetic variants and maternal lifestyle factors. In this article, we focused on the interactions between 13 candidate genes within folate, homocysteine, and transsulfuration pathways for potential association with CTD risk. METHODS: Targeted sequencing was used for 328 case-parental triads enrolled in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31851787
DOI: 10.1002/mgg3.1010
PMCID: PMC6978401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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