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Article

Variants of folate metabolism genes and the risk of conotruncal cardiac defects.

Circulation. Cardiovascular genetics - 1 Dec 2008

Goldmuntz Elizabeth, Woyciechowski Stacy, Renstrom Daniel, Lupo Philip J, Mitchell Laura E

Abstract excerpt

BACKGROUND: Although congenital heart defects (CHD) are the most common and serious group of birth defects, relatively little is known about the causes of these conditions and there are no established prevention strategies. There is evidence suggesting that the risk of CHD in general, and conotruncal and ventricular septal defects in particular, may be related to maternal folate status as well as genetic variants...

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Source

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Identifiers

PMID: 20031554
DOI: 10.1161/CIRCGENETICS.108.796342
PMCID: PMC3035562

Genes

MTHFR

Variants

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