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Article

Assessment of Phenotype Microarray plates for rapid and high-throughput analysis of collateral sensitivity networks.

PloS one - 1 Jan 2019

Dunkley Elsie J, Chalmers James D, Cho Stephanie, Finn Thomas J, Patrick Wayne M

Abstract excerpt

The crisis of antimicrobial resistance is driving research into the phenomenon of collateral sensitivity. Sometimes, when a bacterium evolves resistance to one antimicrobial, it becomes sensitive to others. In this study, we have investigated the utility of Phenotype Microarray (PM) plates for identifying collateral sensitivities with unprecedented throughput. We assessed the relative resistance/sensitivity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31851668
DOI: 10.1371/journal.pone.0219879
PMCID: PMC6919586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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