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Article

Collateral sensitivity of antibiotic-resistant microbes.

Trends in microbiology - 1 Jul 2015

Pál Csaba, Papp Balázs, Lázár Viktória

Abstract excerpt

Understanding how evolution of microbial resistance towards a given antibiotic influences susceptibility to other drugs is a challenge of profound importance. By combining laboratory evolution, genome sequencing, and functional analyses, recent works have charted the map of evolutionary trade-offs between antibiotics and have explored the underlying molecular mechanisms. Strikingly, mutations that caused...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25818802
DOI: 10.1016/j.tim.2015.02.009
PMCID: PMC5958998

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