Article
Role of immune factors in angiotensin II-induced hypertension and renal damage in Dahl salt-sensitive rats.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Mar 2018
Wade Brittany, Petrova Galina, Mattson David L
Abstract excerpt
The present study assessed the importance of immunity in angiotensin (ANG) II (5 ng·kg-1·min-1 iv)-mediated hypertension in Dahl salt-sensitive (SS) rats and SS rats deficient in T and B lymphocytes (SSRag1-/-) fed a 0.4% NaCl diet. Baseline mean arterial blood pressure (MAP) was not different between groups. ANG II infusion significantly increased MAP in both groups, although MAP increased more rapidly in SS...
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