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ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

11 Dec 2019

Abstract excerpt

Computational modeling can be used to investigate complex signaling networks in biology. However, most modeling tools are not suitable for molecular cell biologists with little background in mathematics. We have built a visual-based modeling tool for the investigation of dynamic networks. Here, we describe the development of computational models of cartilage development and osteoarthritis, in which a panel of...

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PMID: 31837466
DOI: 10.1016/j.cellsig.2019.109471

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