Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell RNA sequencing analysis of human chondrocytes reveals cell–cell communication alterations mediated by interactive signaling pathways in osteoarthritis

4 Apr 2023

Abstract excerpt

Objective: Osteoarthritis (OA) is a common joint disorder characterized by degenerative articular cartilage, subchondral bone remodeling, and inflammation. Increasing evidence suggests that the substantial crosstalk between cartilage and synovium is closely related to Osteoarthritis development, but the events that cause this degeneration remain unknown. This study aimed to explore the alterations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Chemokine receptors and signaling
Share to Osteoarthritis Treatment and Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37082621
DOI: 10.3389/fcell.2023.1099287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing analysis of human chondrocytes reveals cell–cell communication alterations mediated by interactive signaling pathways in osteoarthritisPMID 37082621Read ↗

Single-cell profiling uncovers synovial fibroblast subpopulations associated with chondrocyte injury in osteoarthritisSemantic proximity Read ↗

Single-cell RNA seq analysis identifies the biomarkers and differentiation of chondrocyte in human osteoarthritisSemantic proximity Read ↗

Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease ProgressionSemantic proximity Read ↗

A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritisSemantic proximity Read ↗

Single‐cell <scp>RNA</scp> sequencing in osteoarthritisSemantic proximity Read ↗

Single-cell transcriptomic profiling of human knee cartilage reveals branching chondrocyte state transitions and extracellular matrix–centered remodeling in osteoarthritisSemantic proximity Read ↗

Single-cell RNA-seq analysis reveals the progression of human osteoarthritis.Semantic proximity Read ↗

Identifying Novel Osteoarthritis-Associated Genes in Human Cartilage Using a Systematic Meta-Analysis and a Multi-Source Integrated NetworkSemantic proximity Read ↗

Integrated single-cell and bulk RNA sequencing analysis identified pyroptosis-related signature for diagnosis and prognosis in osteoarthritisSemantic proximity Read ↗

Identification of cellular heterogeneity and immunogenicity of chondrocytes via single-cell RNA sequencing technique in human osteoarthritisSemantic proximity Read ↗

Single-cell RNA sequencing reveals the impact of mechanical loading on knee tibial cartilage in osteoarthritisSemantic proximity Read ↗

Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic dataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.