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Article

Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype.

PloS one - 1 Jan 2012

Kerkhofs Johan, Roberts Scott J, Luyten Frank P, Van Oosterwyck Hans, Geris Liesbet

Abstract excerpt

During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a network like structure. In this study, a large-scale literature based logical model of the growt...

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Identifiers

PMID: 22558096
DOI: 10.1371/journal.pone.0034729
PMCID: PMC3340393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22558096-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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