Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive profiling of BRCA1 and BRCA2 variants in breast and ovarian cancer in Chinese patients.

Human mutation - 1 Mar 2020

Gao Xianqi, Nan Xiyan, Liu Yilan, Liu Rui, Zang Wanchun, Shan Guangyu, Gai Fei, Zhang Jingfeng, Li Lei, Cheng Gang, Song Lele

Abstract excerpt

The identification and interpretation of germline BRCA1/2 variants become increasingly important in breast and ovarian cancer (OC) treatment. However, there is no comprehensive analysis of the germline BRCA1/2 variants in a Chinese population. Here we performed a systematic review and meta-analysis on such variants from 94 publications. A total of 2,128 BRCA1/2 variant records were extracted, including 601 from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Breast Neoplasms

Share to Databases, Genetic

Share to Genetic Association Studies

Share to Germ-Line Mutation

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 31825140
DOI: 10.1002/humu.23965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive profiling of BRCA1 and BRCA2 variants in breast and ovarian cancer in Chinese patients.PMID 31825140Read ↗

Prevalence and Spectrum of BRCA1/2 Germline Mutations in Women with Breast Cancer in China Based on Next-Generation Sequencing.Semantic proximity Read ↗

Prevalence of BRCA1/BRCA2 pathogenic variation in Chinese Han population.Semantic proximity Read ↗

Analysis of BRCA1/2 mutation spectrum and prevalence in unselected Chinese breast cancer patients by next-generation sequencing.Semantic proximity Read ↗

<i>BRCA1</i> and <i>BRCA2</i> mutations in ovarian cancer patients from China: ethnic‐related mutations in <i>BRCA1</i> associated with an increased risk of ovarian cancerSemantic proximity Read ↗

The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing.Semantic proximity Read ↗

Prevalence of BRCA1 and BRCA2 pathogenic variants in 8627 unselected patients with breast cancer: stratification of age at diagnosis, family history and molecular subtype.Semantic proximity Read ↗

Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing SuggestionsSemantic proximity Read ↗

The frequency and pathogenicity of BRCA1 and BRCA2 variants in the general Japanese population.Semantic proximity Read ↗

Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian CancerSemantic proximity Read ↗

Retrospective reinterpretation and reclassification of BRCA1/2 variants from Chinese population.Semantic proximity Read ↗

Mutation Spectrum Analysis of BRCA1/2 Genes for Hereditary Breast and Ovarian Cancer in the Indian Population.Semantic proximity Read ↗

Prevalence of hereditary breast and ovarian cancer (HBOC) predisposition gene mutations among 882 HBOC high-risk Chinese individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.