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Prevalence of hereditary breast and ovarian cancer (HBOC) predisposition gene mutations among 882 HBOC high-risk Chinese individuals.

Cancer science - 1 Feb 2020

Shao Di, Cheng Shaomin, Guo Fengming, Zhu Changbin, Yuan Yuying, Hu Kunling, Wang Zhe, Meng Xuan, Jin Xin, Xiong Yun, Chai Xianghua, Li Hong, Zhang Yu, Zhang Hongyun, Liu Jihong, Ye Mingzhi

Abstract excerpt

Identification of deleterious variants in hereditary breast and ovarian cancer (HBOC) susceptibility genes allows for increased clinical surveillance and early detection, and could predict the response to poly (ADP-ribose) polymerase (PARP) inhibitor in patients with advanced ovarian carcinomas. To determine the prevalence and clinical prediction factors for HBOC syndrome, 882 selected individuals underwent...

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PMID: 31742824
DOI: 10.1111/cas.14242
PMCID: PMC7004523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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