Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

doi:10.1136/gutjnl-2019-319313

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Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Gut - 1 Aug 2020

Montazeri Zahra, Li Xue, Nyiraneza Christine, Ma Xiangyu, Timofeeva Maria, Svinti Victoria, Meng Xiangrui, He Yazhou, Bo Yacong, Morgan Samuel, Castellví-Bel Sergi, Ruiz-Ponte Clara, Fernández-Rozadilla Ceres, Carracedo Ángel, Castells Antoni, Bishop Timothy, Buchanan Daniel, Jenkins Mark A, Keku Temitope O, Lindblom Annika, van Duijnhoven Fränzel J B, Wu Anna, Farrington Susan M, Dunlop Malcolm G, Campbell Harry, Theodoratou Evropi, Zheng Wei, Little Julian

Abstract excerpt

OBJECTIVE: To provide an understanding of the role of common genetic variations in colorectal cancer (CRC) risk, we report an updated field synopsis and comprehensive assessment of evidence to catalogue all genetic markers for CRC (CRCgene2). DESIGN: We included 869 publications after parallel literature review and extracted data for 1063 polymorphisms in 303 different genes. Meta-analyses were performed for 308...

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Identifiers

PMID: 31818908
DOI: 10.1136/gutjnl-2019-319313
PMCID: PMC7398467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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