Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.

doi:10.1038/ng.2505

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Article

Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.

Nature genetics - 1 Feb 2013

Jia Wei-Hua, Zhang Ben, Matsuo Keitaro, Shin Aesun, Xiang Yong-Bing, Jee Sun Ha, Kim Dong-Hyun, Ren Zefang, Cai Qiuyin, Long Jirong, Shi Jiajun, Wen Wanqing, Yang Gong, Delahanty Ryan J, Ji Bu-Tian, Pan Zhi-Zhong, Matsuda Fumihiko, Gao Yu-Tang, Oh Jae Hwan, Ahn Yoon-Ok, Park Eun Jung, Li Hong-Lan, Park Ji Won, Jo Jaeseong, Jeong Jin-Young, Hosono Satoyo, Casey Graham, Peters Ulrike, Shu Xiao-Ou, Zeng Yi-Xin, Zheng Wei

Abstract excerpt

To identify new genetic factors for colorectal cancer (CRC), we conducted a genome-wide association study in east Asians. By analyzing genome-wide data in 2,098 cases and 5,749 controls, we selected 64 promising SNPs for replication in an independent set of samples, including up to 5,358 cases and 5,922 controls. We identified four SNPs with...

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PMID: 23263487
DOI: 10.1038/ng.2505
PMCID: PMC3679924

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CCND2

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