Article
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
British journal of cancer - 19 Jan 2010
Tomlinson I P M, Dunlop M, Campbell H, Zanke B, Gallinger S, Hudson T, Koessler T, Pharoah P D, Niittymäki I, Niittymäkix I, Tuupanen S, Tuupanenx S, Aaltonen L A, Hemminki K, Lindblom A, Försti A, Sieber O, Lipton L, van Wezel T, Morreau H, Wijnen J T, Devilee P, Matsuda K, Nakamura Y, Castellví-Bel S, Ruiz-Ponte C, Castells A, Carracedo A, Ho J W C, Sham P, Hofstra R M W, Vodicka P, Brenner H, Hampe J, Schafmayer C, Tepel J, Schreiber S, Völzke H, Lerch M M, Schmidt C A, Buch S, Moreno V, Villanueva C M, Peterlongo P, Radice P, Echeverry M M, Velez A, Carvajal-Carmona L, Scott R, Penegar S, Broderick P, Tenesa A, Houlston R S
Abstract excerpt
It is now recognised that a part of the inherited risk of colorectal cancer (CRC) can be explained by the co-inheritance of low-penetrance genetic variants. The accumulated experience to date in identifying these variants has served to highlight difficulties in conducting statistically and methodologically rigorous studies and follow-up analyses. The COGENT (COlorectal cancer GENeTics) consortium includes 20...
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