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Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

Gut - 1 Feb 2014

Ma Xiangyu, Zhang Ben, Zheng Wei

Abstract excerpt

OBJECTIVE: In the past two decades, approximately 1000 reports have been published regarding associations between genetic variants in candidate genes and risk of colorectal cancer (CRC). Study results are inconsistent. We aim to provide a synopsis of the current understanding of genetic factors for CRC risk through systematically evaluating results from previous studies. DESIGN: We searched PubMed and Google...

Topics

Colon
Colorectal Neoplasms
Genetic Predisposition to Disease
Genetic Variation
Humans
Risk Assessment
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23946381
DOI: 10.1136/gutjnl-2012-304121
PMCID: PMC4020522

Genes

APC
CHEK2
GSTM1
MLH1
MUTYH
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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