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Article

AKT1 and genetic vulnerability to bipolar disorder.

Psychiatry research - 1 Feb 2020

Millischer Vincent, Matheson Granville J, Martinsson Lina, Römer Ek Inger, Schalling Martin, Lavebratt Catharina, Backlund Lena

Abstract excerpt

AKT1 encodes a serine/threonine kinase that has as one of its best-known substrates glycogen synthase kinase-3 (GSK3), a primary target for lithium. AKT1 has been previously been implicated as a vulnerability gene for bipolar disorder (BD). We aimed to associate genetic variants in the AKT1 gene with subgroups of BD. BD patients from a Swedish cohort (N = 831) were phenotyped in regards to their psychotic...

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Source

Identifiers

PMID: 31810747
DOI: 10.1016/j.psychres.2019.112677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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