Article
Association between AKT1 but not AKTIP genetic variants and increased risk for suicidal behavior in bipolar patients.
Genes, brain, and behavior - 1 Jun 2010
Magno L A V, Miranda D M, Neves F S, Pimenta G J, Mello M P, De Marco L A, Correa H, Romano-Silva M A
Abstract excerpt
We tested the hypothesis that the presence of AKT1 and AKTIP polymorphisms, target genes that encode key proteins in the signaling of dopaminergic and serotonergic systems, is associated with suicidal behavior in bipolar patients. The subjects were 273 patients diagnosed with bipolar disorder I or II (age = 41.4 +/- 12.9). TaqMan single-nucleotide polymorphism genotyping assays (AKT1: rs2494731, rs3803304,...
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