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Health Implications Associated with Fat-Free Mass: A Phenome-Wide Mendelian Randomization Study.

Cardiorenal medicine - 1 Jan 2025

Ying Yuchen, Zhang Chunxia, Wu Shanshan, Wang Shudan, Lian Jiangfang, Lin Yupin, Guan Haiwang, Cai Dihui

Abstract excerpt

INTRODUCTION: Fat-free mass (FFM) is a critical component of the human body, with implications for various diseases. METHODS: We conducted a comprehensive analysis integrating a phenome-wide association study (PheWAS), a two-sample Mendelian randomization (MR) analysis, and a systematic review to investigate the associations between FFM and health outcomes. RESULTS: PheWAS identified 183 phenotypes enriched for...

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PMID: 40179848
DOI: 10.1159/000545641

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