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Article

Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies.

Scientific reports - 19 Mar 2020

Ran Shu, Jiang Zi-Xuan, He Xiao, Liu Yu, Zhang Yu-Xue, Zhang Lei, Pei Yu-Fang, Zhang Meng, Hai Rong, Gu Gui-Shan, Liu Bao-Lin, Tian Qing, Zhang Yong-Hong, Wang Jing-Yu, Deng Hong-Wen

Abstract excerpt

Sarcopenia is characterized by low skeletal muscle, a complex trait with high heritability. With the dramatically increasing prevalence of obesity, obesity and sarcopenia occur simultaneously, a condition known as sarcopenic obesity. Fat mass and obesity-associated (FTO) gene is a candidate gene of obesity. To identify associations between lean mass and FTO gene, we performed a genome-wide association study...

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Identifiers

PMID: 32193455
DOI: 10.1038/s41598-020-61406-3
PMCID: PMC7081265

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