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Article

Genomic Underpinnings of Tumor Behavior in In Situ and Early Lung Adenocarcinoma.

American journal of respiratory and critical care medicine - 15 Mar 2020

Qian Jun, Zhao Shilin, Zou Yong, Rahman S M Jamshedur, Senosain Maria-Fernanda, Stricker Thomas, Chen Heidi, Powell Charles A, Borczuk Alain C, Massion Pierre P

Abstract excerpt

Rationale: We have a limited understanding of the molecular underpinnings of early adenocarcinoma (ADC) progression. We hypothesized that the behavior of early ADC can be predicted based on genomic determinants.Objectives: To identify genomic alterations associated with resected indolent and aggressive early lung ADCs.Methods: DNA was extracted from 21 ADCs in situ (AISs), 27 minimally invasive ADCs (MIAs), and...

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Identifiers

PMID: 31747302
DOI: 10.1164/rccm.201902-0294OC
PMCID: PMC7068818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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