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Article

Elucidating Genomic Characteristics of Lung Cancer Progression from In Situ to Invasive Adenocarcinoma.

Scientific reports - 22 Aug 2016

Vinayanuwattikun Chanida, Le Calvez-Kelm Florence, Abedi-Ardekani Behnoush, Zaridze David, Mukeria Anush, Voegele Catherine, Vallée Maxime, Purnomosari Dewajani, Forey Nathalie, Durand Geoffroy, Byrnes Graham, Mckay James, Brennan Paul, Scelo Ghislaine

Abstract excerpt

To examine the diversity of somatic alterations and clonal evolution according to aggressiveness of disease, nineteen tumor-blood pairs of 'formerly bronchiolo-alveolar carcinoma (BAC)' which had been reclassified into preinvasive lesion (adenocarcinoma in situ; AIS), focal invasive lesion (minimally invasive adenocarcinoma; MIA), and invasive lesion (lepidic predominant adenocarcinoma; LPA and non-lepidic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27545006
DOI: 10.1038/srep31628
PMCID: PMC4992872

Genes

LPA
MIA
KRAS
RBM10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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