Article
Genomic signature driving preinvasive to invasive processes in stage I lung adenocarcinoma.
International journal of cancer - 1 Apr 2026
Mou Biqin, Duan Yishan, Wang Jing, Li Tiantian, Huo Yuwei, Xiao Xia, Cui Conghui, Deng Zhujun, Hu Qiongxia, Jiang Juan, Liang Yiwei, Lu Sifen, Tao Xintong, Xie Kang, Xiong Xinru, Zhu Niu, Bi Liyun, Zhang Faqiang, Li Weimin, Chen Bojiang
Abstract excerpt
Progression from minimally invasive adenocarcinoma (MIA) to invasive adenocarcinoma (IA) in lung adenocarcinoma (LUAD) is associated with a significantly worse prognosis and lacks predictive markers. The genomic molecular mechanisms of progression and genetic signatures mediating the MIA to IA transition in early-stage LUAD are still largely uncharacterized. In our study, a genomic signature driving MIA to IA was...
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