Article
Interleukin-38 alleviates cardiac remodelling after myocardial infarction.
Journal of cellular and molecular medicine - 1 Jan 2020
Wei Yuzhen, Lan Yin, Zhong Yucheng, Yu Kunwu, Xu Wenbin, Zhu Ruirui, Sun Haitao, Ding Yan, Wang Yue, Zeng Qiutang
Abstract excerpt
Excessive immune-mediated inflammatory reaction plays a deleterious role in ventricular remodelling after myocardial infarction (MI). Interleukin (IL)-38 is a newly characterized cytokine of the IL-1 family and has been reported to exert a protective effect in some autoimmune diseases. However, its role in cardiac remodelling post-MI remains unknown. In this study, we found that the expression of IL-38 was...
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