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Article

Activated T Lymphocytes are Essential Drivers of Pathological Remodeling in Ischemic Heart Failure.

Circulation. Heart failure - 1 Mar 2017

Bansal Shyam S, Ismahil Mohamed Ameen, Goel Mehak, Patel Bindiya, Hamid Tariq, Rokosh Gregg, Prabhu Sumanth D

Abstract excerpt

BACKGROUND: Inappropriately sustained inflammation is a hallmark of chronic ischemic heart failure (HF); however, the pathophysiological role of T lymphocytes is unclear. METHODS AND RESULTS: Permanent coronary ligation was performed in adult C57BL/6 mice. When compared with sham-operated mice, mice with HF (8 weeks after ligation) exhibited the following features: (1) significant (P<0.05) expansion of...

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Identifiers

PMID: 28242779
DOI: 10.1161/CIRCHEARTFAILURE.116.003688
PMCID: PMC5331621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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