Article
Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants.
European journal of cancer (Oxford, England : 1990) - 1 Jan 2020
Summers Matthew G, Maughan Timothy S, Kaplan Richard, Law Philip J, Houlston Richard S, Escott-Price Valentina, Cheadle Jeremy P
Abstract excerpt
PURPOSE: Genome-wide association studies have identified common single nucleotide polymorphisms (SNPs) at 83 loci associated with colorectal cancer (CRC) risk in European populations. Because germline variation can also influence patient outcome, we studied the relationship between these SNPs and CRC survivorship. EXPERIMENTAL DESIGN: For the 83 risk loci, 10 lead SNPs were directly genotyped, 72 were imputed and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
