Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis.

doi:10.1093/carcin/bgv161

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Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis.

Carcinogenesis - 1 Jan 2016

Phipps Amanda I, Passarelli Michael N, Chan Andrew T, Harrison Tabitha A, Jeon Jihyoun, Hutter Carolyn M, Berndt Sonja I, Brenner Hermann, Caan Bette J, Campbell Peter T, Chang-Claude Jenny, Chanock Stephen J, Cheadle Jeremy P, Curtis Keith R, Duggan David, Fisher David, Fuchs Charles S, Gala Manish, Giovannucci Edward L, Hayes Richard B, Hoffmeister Michael, Hsu Li, Jacobs Eric J, Jansen Lina, Kaplan Richard, Kap Elisabeth J, Maughan Timothy S, Potter John D, Schoen Robert E, Seminara Daniela, Slattery Martha L, West Hannah, White Emily, Peters Ulrike, Newcomb Polly A

Abstract excerpt

Genome-wide association studies have identified several germline single nucleotide polymorphisms (SNPs) significantly associated with colorectal cancer (CRC) incidence. Common germline genetic variation may also be related to CRC survival. We used a discovery-based approach to identify SNPs related to survival outcomes after CRC diagnosis. Genome-wide genotyping arrays were conducted for 3494 individuals with...

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PMID: 26586795
DOI: 10.1093/carcin/bgv161
PMCID: PMC4715234

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