Article
GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis.
European journal of cancer (Oxford, England : 1990) - 1 Jul 2011
Xing Jinliang, Myers Ronald E, He Xianli, Qu Falin, Zhou Feng, Ma Xi, Hyslop Terry, Bao Guoqiang, Wan Shaogui, Yang Hushan, Chen Zhinan
Abstract excerpt
PURPOSE: Extensive evidence has suggested that risk factors of cancer development may also modulate cancer clinical outcome. Recent genome-wide association (GWA) studies identified several single nucleotide polymorphisms (SNPs) predisposing to colorectal cancer (CRC). Given the pivotal importance of these variants in CRC, we sought to evaluate their associations with clinical outcomes of the disease. EXPERIMENTAL...
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