Article
Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival.
Scientific reports - 7 Jan 2022
Labadie Julia D, Savas Sevtap, Harrison Tabitha A, Banbury Barb, Huang Yuhan, Buchanan Daniel D, Campbell Peter T, Gallinger Steven J, Giles Graham G, Gunter Marc J, Hoffmeister Michael, Hsu Li, Jenkins Mark A, Lin Yi, Ogino Shuji, Phipps Amanda I, Slattery Martha L, Steinfelder Robert S, Sun Wei, Van Guelpen Bethany, Hua Xinwei, Figuieredo Jane C, Pai Rish K, Nassir Rami, Qi Lihong, Chan Andrew T, Peters Ulrike, Newcomb Polly A
Abstract excerpt
Identification of new genetic markers may improve the prediction of colorectal cancer prognosis. Our objective was to examine genome-wide associations of germline genetic variants with disease-specific survival in an analysis of 16,964 cases of colorectal cancer. We analyzed genotype and colorectal cancer-specific survival data from a consortium of 15 studies. Approximately 7.5 million SNPs were examined under...
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