Article
Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2015
Smith Christopher G, Fisher David, Harris Rebecca, Maughan Timothy S, Phipps Amanda I, Richman Susan, Seymour Matthew, Tomlinson Ian, Rosmarin Dan, Kerr David, Chan Andrew T, Peters Ulrike, Newcomb Polly A, Idziaszczyk Shelley, West Hannah, Meade Angela, Kaplan Richard, Cheadle Jeremy P
Abstract excerpt
PURPOSE: Genome-wide association studies have identified numerous loci associated with colorectal cancer risk. Several of these have also been associated with patient survival, although none have been validated. Here, we used large independent training and validation cohorts to identify robust prognostic biomarkers for colorectal cancer. EXPERIMENTAL DESIGN: In our training phase, we analyzed 20 colorectal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.