Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer.

doi:10.1158/1078-0432.CCR-19-2390

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Article

Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2020

Datta Jashodeep, Smith J Joshua, Chatila Walid K, McAuliffe John C, Kandoth Cyriac, Vakiani Efsevia, Frankel Timothy L, Ganesh Karuna, Wasserman Isaac, Lipsyc-Sharf Marla, Guillem Jose, Nash Garrett M, Paty Philip B, Weiser Martin R, Saltz Leonard B, Berger Michael F, Jarnagin William R, Balachandran Vinod, Kingham T Peter, Kemeny Nancy E, Cercek Andrea, Garcia-Aguilar Julio, Taylor Barry S, Viale Agnes, Yaeger Rona, Solit David B, Schultz Nikolaus, D'Angelica Michael I

Abstract excerpt

PURPOSE: We aimed to investigate genomic correlates underlying extremes of survivorship in metastatic colorectal cancer and their applicability in informing survival in distinct subsets of patients with metastatic colorectal cancer. EXPERIMENTAL DESIGN: We examined differences in oncogenic somatic alterations between metastatic colorectal cancer cohorts demonstrating extremes of survivorship following complete...

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PMID: 31719050
DOI: 10.1158/1078-0432.CCR-19-2390
PMCID: PMC7056517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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