Article
Association of genomic profiles and survival in early onset and screening-age colorectal cancer patients with liver metastases resected over 15 years.
Journal of surgical oncology - 1 Apr 2022
Narayan Raja R, Aveson Victoria G, Chou Joanne F, Walch Henry S, Sanchez-Vega Francisco, Santos Fernandes Gustavo Dos, Balachandran Vinod P, D'Angelica Michael I, Drebin Jeffrey A, Jarnagin William R, Wei Alice C, Cercek Andrea, Gönen Mithat, Schultz Nikolaus, Kingham T Peter
Abstract excerpt
BACKGROUND: This study explores whether genomic profiles of colorectal liver metastasis (CRLM) patients with early onset (EO, < 50 years old) and screening age (SA) primary diagnosis are associated with overall survival (OS). METHODS: All patients undergoing hepatectomy between 2002 and 2017 were identified and tumor specimens with next-generation sequencing data were cataloged. Gene and signaling-level...
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