TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.

doi:10.1111/adb.12838

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.

Addiction biology - 1 Jan 2021

Wiers Corinde E, Martins De Carvalho Luana, Hodgkinson Colin A, Schwandt Melanie, Kim Sung Won, Diazgranados Nancy, Wang Gene-Jack, Goldman David, Volkow Nora D

Abstract excerpt

The translocator protein (TSPO) transports cholesterol into mitochondria and is involved in steroidogenesis. The TSPO polymorphism rs6971 influences binding of cholesterol and other TSPO ligands including positron-emission tomography (PET) imaging radiotracers. Although it is recognized that alcohol increases plasma high-density lipoproteins (HDLs), its effects on total cholesterol and triglycerides along with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Positron-Emission Tomography

Share to Receptors, GABA

Share to Substance Withdrawal Syndrome

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 31713961
DOI: 10.1111/adb.12838
PMCID: PMC7214120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.PMID 31713961Read ↗

TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.Semantic proximity Read ↗

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO).Semantic proximity Read ↗

Variation rs6971 in the Translocator Protein Gene (TSPO) is Associated with Aggressiveness and Impulsivity but Not with Anxiety in a Population-Representative Sample of Young Adults.Semantic proximity Read ↗

Elevated transferrin saturation in individuals with alcohol use disorder: Association with HFE polymorphism and alcohol withdrawal severity.Semantic proximity Read ↗

Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder.Semantic proximity Read ↗

The OXT rs6133010 variant modulates susceptibility to psychiatric symptoms during withdrawal in patients with alcohol dependence.Semantic proximity Read ↗

In vivo imaging of translocator protein, a marker of activated microglia, in alcohol dependence.Semantic proximity Read ↗

Genetic susceptibility to telomere shortening through the rs2293607 polymorphism is associated with a greater risk of alcohol use disorder.Semantic proximity Read ↗

Differential mitochondrial protein interaction profile between human translocator protein and its <i>A147T</i> polymorphism variantSemantic proximity Read ↗

Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism.Semantic proximity Read ↗

Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype.Semantic proximity Read ↗

A review of genetic, biological, pharmacological, and clinical factors that affect carbohydrate-deficient transferrin levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.