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Article

The OXT rs6133010 variant modulates susceptibility to psychiatric symptoms during withdrawal in patients with alcohol dependence.

BMC psychiatry - 3 Feb 2025

Shen Guanghui, Wang Wei, Wu Yuyu, Luo Xinguang, Wang Kexin, Chen Yu-Hsin, Kang Yimin, Liu Yanlong, Wang Fan, Chen Li

Abstract excerpt

BACKGROUND: Alcohol dependence (AD) confers susceptibility to distressing withdrawal symptoms that often lead to relapse. While neuroadaptation during withdrawal influences symptoms, the genetic factors behind it have not been thoroughly investigated. We utilized propensity score matching and investigated connections between AD, OXT rs6133010, and withdrawal symptoms to address confounding variables. By...

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Identifiers

PMID: 39901079
DOI: 10.1186/s12888-025-06529-5
PMCID: PMC11792688

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OXT

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