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Article

Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder.

Psychoneuroendocrinology - 1 Mar 2018

Prossin Alan R, Chandler Matthew, Ryan Kelly A, Saunders Erika F, Kamali Masoud, Papadopoulos Vassilios, Zöllner Sebastian, Dantzer Robert, McInnis Melvin G

Abstract excerpt

INTRODUCTION: Psychosocial stress contributes to onset/exacerbation of mood episodes and alcohol use, suggesting dysregulated diurnal cortisol rhythms underlie episodic exacerbations in Bipolar Disorder (BD). However, mechanisms underlying dysregulated HPA rhythms in BD and alcohol use disorders (AUD) are understudied. Knowledge of associated variance factors have great clinical translational potential by...

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Identifiers

PMID: 29414032
DOI: 10.1016/j.psyneuen.2018.01.013
PMCID: PMC6048960

Genes

TSPO

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