Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elevated transferrin saturation in individuals with alcohol use disorder: Association with HFE polymorphism and alcohol withdrawal severity.

Addiction biology - 1 Mar 2022

Kroll Danielle S, McPherson Katherine L, Manza Peter, Schwandt Melanie L, Shen Pei-Hong, Goldman David, Diazgranados Nancy, Wang Gene-Jack, Wiers Corinde E, Volkow Nora D

Abstract excerpt

Iron loading has been consistently reported in those with alcohol use disorder (AUD), but its effect on the clinical course of the disease is not yet fully understood. Here, we conducted a cohort study to examine whether peripheral iron measures, genetic variation in HFE rs1799945 and their interaction differed between 594 inpatient participants with alcohol use disorder (AUD) undergoing detoxification and 472...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genotype

Share to Hemochromatosis Protein

Share to Iron Overload

Share to Substance Withdrawal Syndrome

Share to Transferrin

Source

Open in PubMed Open full text

Identifiers

PMID: 35229939
DOI: 10.1111/adb.13144
PMCID: PMC9373047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elevated transferrin saturation in individuals with alcohol use disorder: Association with HFE polymorphism and alcohol withdrawal severity.PMID 35229939Read ↗

Effects of alcohol consumption on indices of iron stores and of iron stores on alcohol intake markers.Semantic proximity Read ↗

A review of genetic, biological, pharmacological, and clinical factors that affect carbohydrate-deficient transferrin levels.Semantic proximity Read ↗

TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.Semantic proximity Read ↗

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analysesSemantic proximity Read ↗

Hfe mutations and iron overload in patients with alcoholic liver disease.Semantic proximity Read ↗

FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice.Semantic proximity Read ↗

Ferroportin Q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption.Semantic proximity Read ↗

Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population.Semantic proximity Read ↗

Effects of HFE gene mutations and alcohol on iron status, liver biochemistry and morbidity.Semantic proximity Read ↗

Non-HFE iron overload as a surrogate marker of disease severity in patients of liver cirrhosis.Semantic proximity Read ↗

HFE genotypes in decompensated alcoholic liver disease: phenotypic expression and comparison with heavy drinking and with normal controls.Semantic proximity Read ↗

Illustration of a Novel Gut-Brain Axis of Alcohol Withdrawal, Withdrawal-Associated Depression, Craving and Alcohol-Severity Index in Alcohol Use Disorder PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.